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| 周围神经损伤与再生的可视化研究 | |
| 引用本文： | 陈菁,彭承琳,楚燕飞,朱刚,李兵仓,赵辉,陈志强. 周围神经损伤与再生的可视化研究[J]. 生物医学工程学杂志, 2005, 22(2): 324-326 |
| 作者姓名： | 陈菁 彭承琳 楚燕飞 朱刚 李兵仓 赵辉 陈志强 |
| 作者单位： | 1. 重庆大学,生物工程学院,重庆,400044;第三军医大学,野战外科研究所,重庆,400042 2. 重庆大学,生物工程学院,重庆,400044 3. 第三军医大学,西南医院神经外科,重庆,400038 4. 第三军医大学,野战外科研究所,重庆,400042 |
| 基金项目： | 国家 973创伤基础研究资助项目 (G19990 5 42 0 6) |
| 摘 要： | 周围神经损伤后其远近端形态改变与神经再生及功能恢复有密切联系。本试验通过硅胶管桥接大鼠坐骨神经缺损模型,对不同时间点、损伤区不同部位的坐骨神经进行连续切片,光、电镜观察摄像后,利用计算机图像重建技术,采用体素模型在SGI三维图形工作站上对大鼠坐骨神经损伤后变性、再生过程中形态结构改变进行三维重建和显示。三维图像显示新生神经纤维与正常神经纤维相比有郎飞氏结尚未形成、排列紊乱、髓鞘较薄、轴索较细、胶原纤维增生等差异。 |
| 关 键 词： | 周围神经 三维重建 可视化 |
| 收稿时间： | 2002-11-04 |
| 修稿时间： | 2002-11-042003-05-06 |
Visualization of Regenerated Sciatic Nerve of Rat After Injury |
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| Chen Jing,Peng Chenglin,Chu Yanfei,Zhu Gang,Li Bingcang,Zhao Hui,Chen Zhiqiang. Visualization of Regenerated Sciatic Nerve of Rat After Injury[J]. Journal of biomedical engineering, 2005, 22(2): 324-326 | |
| Authors: | Chen Jing Peng Chenglin Chu Yanfei Zhu Gang Li Bingcang Zhao Hui Chen Zhiqiang |
| Affiliation: | 1 Bioengineering Institute, Chongqing University, Chongqing 400044,China;2 Institute of Surgery, Third Military Medical University, Chongqing 400042,China;3 Department of Neurosurgery, Xinan Hospital, Third Military Medical University, Chongqing 400038,China |
| Abstract: | There is close relationship between the morphologic change s of periphe ral nerve after injury and its function recovery during regeneration. In our exp eriment, the sciatic nerve of rats was transected and bridge-connected with sil i cone tube, and the images of serial slices of different time and different injur y parts were taken by micro-photograph system. The volume unit model was applie d to rendering the three dimensional (3D) structure of degenerative and regenerat ive sciatic nerve fiber and its affiliated structure after injury. The 3D images showed that node of Ranvier had not formed and its array was turbulent, both th e myelin sheath and the axis-cylinder were thinner, and the collagen fibres had proliferated. |
| Keywords: | Peripheral nerve 3D reconstruction Visualization |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |