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Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are increased in Alzheimer's disease
Authors:Per Johansson  Daniel Åberg  Jan-Ove Johansson  Niklas Mattsson  Oskar Hansson  Bo Ahrén  Jörgen Isgaard  N David Åberg  Kaj Blennow  Henrik Zetterberg  Anders Wallin  Johan Svensson
Institution:1. Department of Neuropsychiatry, Skaraborg Hospital, SE-521 85 Falköping, Sweden;2. Department of Internal Medicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden;3. Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at University of Gothenburg, SE-431 80 Mölndal, Sweden;4. Clinical Memory Research Unit, Department of Clinical Sciences, Skåne University Hospital, Lund University, SE-205 02 Malmö, Sweden;5. Department of Clinical Sciences, Lund University, SE-221 84, Sweden;6. UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK;g Department of Endocrinology, Skaraborg Hospital, SE-541 85 Skövde, Sweden
Abstract:
Keywords:IGF-I  IGFBP-3  Insulin  Cerebrospinal fluid  Alzheimer's disease  Mild cognitive impairment  AD biomarker
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