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Plasma metabolites after 2-deoxy-D-glucose in rats with brain dopamine-depleting lesions
Authors:Neil Rowland  Angelyn Bales
Institution:Department of Psychology, University of Florida, Gainesville, FL 32611 USA
Abstract:Rats with selective brain dopamine-depleting lesions produced by 6-hydroxydopamine failed to increase their food intake after 2-deoxy-D-glucose administration. Their hyperglycemic response to 2DG was identical to that of intact controls. Neither group showed significant mobilization of free fatty acids or production of ketones.
Keywords:Dopamine  6-Hydroxydopamine  2-Deoxy-D-glucose  Metabolic fuels
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