Plasma metabolites after 2-deoxy-D-glucose in rats with brain dopamine-depleting lesions |
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Authors: | Neil Rowland Angelyn Bales |
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Institution: | Department of Psychology, University of Florida, Gainesville, FL 32611 USA |
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Abstract: | Rats with selective brain dopamine-depleting lesions produced by 6-hydroxydopamine failed to increase their food intake after 2-deoxy-D-glucose administration. Their hyperglycemic response to 2DG was identical to that of intact controls. Neither group showed significant mobilization of free fatty acids or production of ketones. |
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Keywords: | Dopamine 6-Hydroxydopamine 2-Deoxy-D-glucose Metabolic fuels |
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