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诱发电位对2型糖尿病患者视觉功能的损害(英文)
引用本文:陈薇,陈璇,陈慎仁,吴静珊,罗毅平.诱发电位对2型糖尿病患者视觉功能的损害(英文)[J].中国组织工程研究与临床康复,2003,7(10):1540-1541.
作者姓名:陈薇  陈璇  陈慎仁  吴静珊  罗毅平
作者单位:1. 汕头大学医学院第二附属医院神经内科,广东省汕头市,515041
2. 汕头大学医学院第二附属医院神经电生理检查室,广东省汕头市,515041
3. 汕头大学医学院第二附属医院内分泌科,广东省汕头市,515041
基金项目:广东省卫生厅科研项目(编号A1988435)~~
摘    要:目的通过对2型糖尿病患者进行视觉诱发电位(VEP)的检测,了解患者视觉中枢受损程度以及相关因素。方法用NicoletVikingⅣ型肌电图/诱发电位仪对30例2型糖尿病患者(DM组)及年龄和性别与之匹配的健康正常体检者30例(对照组)进行视觉诱发电位的检测应用SPSS统计软件采用t检验和直线相关分析的方法比较两组间VEP各项参数的差异,分析DM组VEP各项参数的变化与病程、血糖、血脂、肾功能之间的关系。结果DM组20例(66.7%)有异常,与对照组比较P100潜伏期明显延长(F=14.417,P<0.01),波幅下降无显著性差异(F=2.886,P>0.05)。DM组VEP参数的改变与血糖、肾功能损害相关(t=3.7069,r=-0.370,χ2=4.00,P<0.05)。结论VEP检测能较早期的反映患者视觉中枢的病变。控制血糖、保护肾功能有利于减轻患者视觉中枢的损害。

关 键 词:糖尿病  诱发电位  视觉

Study of visual function impair evoked potential in type 2 diabetes mellitus
Chen Wei ,Chen Xuan ,Chen Shenren ,Wu Jingshan ,Luo Yiping , De-partment of Neurology.Study of visual function impair evoked potential in type 2 diabetes mellitus[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2003,7(10):1540-1541.
Authors:Chen Wei  Chen Xuan  Chen Shenren  Wu Jingshan  Luo Yiping  De-partment of Neurology
Institution:Chen Wei 1,Chen Xuan 3,Chen Shenren 2,Wu Jingshan 1,Luo Yiping 2,1 De-partment of Neurology,2 Department of Endocrinology,3 Department of Electrophysiologic Study,Affilia ted Second Hospital,Medical College of Shantou University,Shantou 515041,Guangdong Province,China
Abstract:Aim To study the impair degree of visual center and related factors by detection of visual evoked potential(VEP) in patients with type 2 diabetes.Methods Detection of visual evoked potential was performed for 30 patients with type 2 diabetes(DM group) and 30 healthy subjects(control group) who were matched with DM group at age and sex.The differences of parameters between two groups were compared by t test and linear correlation analysis adopting SPSS statistical software and the relationship between changes of VEP parameters in DM group and disease course,blood sugar,blood - lipid and renal function in DM group were analyzed.Results Abnormalities were found in 20 cases(66.7% ),with prolongation of P100 latent period(F=14.417,P< 0.01) and lowering of amplitude of wave(F=2.886,P >0.05) compared with those in control group.Changes of VEP parameters in DM group were related to blood sugar and impairment of renal function(t=3.7069,r=0.370,χ 2=4.00,P< 0.05).Conclusion VEP detection can reflect lesions of visual center in early stage.Controling blood sugar and protecting renal function will do good to alleviation of visual function impairment.
Keywords:diabetes mellitus  evoked potentia l  vision  
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