| 创伤性脑损伤后神经细胞凋亡的基因调控与干预 |
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| 引用本文： | 冰峰,苏宁. 创伤性脑损伤后神经细胞凋亡的基因调控与干预[J]. 内蒙古医学杂志, 2009, 41(2): 201-203 |
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| 作者姓名： | 冰峰 苏宁 |
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| 作者单位： | 内蒙古医学院研究生院,内蒙古,呼和浩特,010059;内蒙古自治区医院神经外科,内蒙古,呼和浩特,010017 |
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| 摘 要： | 创伤性脑损伤后继发性损伤因素可导致神经细胞凋亡的发生,凋亡是脑损伤后脑细胞死亡的重要原因,凋亡相关基因的研究是解决细胞凋亡机制根本,该凋亡过程受bcl-2,caspase,p53,以及早期反应基因等调控,凋亡对脑损伤预后有重要地作用,通过主动对基因调控进行干预,抑制脑细胞凋亡,从而达到脑保护的作用。
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| 关 键 词： | 创伤性脑损伤 凋亡 基因 |
Gene Regulation and Intervention of the Nerve Cell Apoptotic in Traumatic Brain Injury |
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| BING Feng,SU Ning. Gene Regulation and Intervention of the Nerve Cell Apoptotic in Traumatic Brain Injury[J]. Inner Mongolia Medical Journal, 2009, 41(2): 201-203 |
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| Authors: | BING Feng SU Ning |
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| Affiliation: | BING Feng, SU Ning (1. Deparement of Graduate School , The Inner Mongolia Medical College, Huhhot 010059 China ; 2. Deparment of Central, Inner Mongolia Hospital, Huhhot 010017 China ) |
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| Abstract: | Secondary injury factors could cause nerve cell apoptotic after traumatic brain injury, cell apoptbtic is important reason which contributes to brain cell death. Relevant research of gene to solve cell apoptotic is ultimately mechanism, this process is regulated by bcl - 2, caspase, p53, immediate early genes and others genes. Apoptotic have important function on the prognosis of traumatic brain injury. Through initiative intervention gene regulation and depress nerve cell apoptotic, thus reach the protective function of the brain. |
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| Keywords: | Traumatic brain injury Apoptotic Genes |
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