经皮消融配合三维适形放疗治疗原发性肝癌的疗效分析

目的：观察经皮消融配合三维适形放疗治疗原发性肝癌的疗效.方法：45例原发性肝癌随机分成综合组和对照组.综合组21例,采用经皮消融三维适形放疗,对照组单用经皮消融.结果：综合组的局控率为85.7%,而对照组为58.3%,两者有显著性差异.1,2,3年的生存率综合组和对照组分别是81%,62.5%,25%;71.8%,33%,8%.两者差异有统计学意义.结论：原发性肝癌三维适形放疗结合经皮消融疗效较好.

Analysis of three dimensional conformal radiationtherapy with percutaneors ablation for primary hepatic carcinome

Objective：To evaluate the effect of three dimensional conformal radiation（3DCRT） with percutaneous ablation（PA） for unresectable primary hepatic carcinoma. Methods ：Total of 45 patients with primary hepatic carcinoma were randomized to 2 groups： 21 patients were treated with 3DCRT plus PA and the rest （control） were treated with PA only. For 3DCRT, radiation was given by 8MV -x- ray,patients received a total dose of 40 -50Gy, 5Gy per session every other day. Results：the 1,2,3 year survival rates of 3DCRT plus PA group and control group were 81% ,62.5% ,25% ;71.8% ,33% ,8%. The difference between the two groups was significant. The response rate （ CR ＋ PR） of 3DCRT plus PA and PA alone group were 85.7% and 58.3%. The difference was statistically significant. Conclusion：three dimensional conformal radiotherapy combined with PA is effective for unresectable primary liver cancer.