早期Alzheimer病的认知与社会功能的动态观察

目的 :探讨Alzheimer病早期的认知损害与社会功能缺损的特点及相互关系。方法 :对 2 2例早期Alzheimer病患者进行 3个月的观察 ,采用智能筛检测验和功能活动问卷作认知及社会功能活动评估 ,同时与 12例同期的老年期抑郁症患者进行对照。结果 :Alzheimer病患者的认知测验在短时记忆、注意能力、数字计算、抽象判断、思维流畅等因子评分降低更明显 ,而测试所消耗的时间相对较短 ;社会功能活动也以自行购物、了解新鲜事物、记得约定等方面评分较高。治疗后无显著改善。结论 :Alzheimer病患者某些方面的认知功能早期就有显著下降 ,相应的社会功能缺损也较明显

Functional Activity and Cognitive Impairment of Patients with Alzh eimer Disease in its Early Stage

Objective:to study cognitive impairment and social function of patients with Alzheimer disease (AD). Method:22 patients with AD and 12 with depression in elderly were followed for 3 months, both at the very beginning and the end of 3 months, they were tested with CASI (cognitive abilities screening instrument) and FAQ (functional activities questionnaire).Result:scores of short memory, attention, mathematics, abstract and association of CASI were significantly lower in AD group than that in depression group. AD patients had also poorer outcome in FAQ, such as in that of shopping, learn new things, and recall of engagement.Conclusion:Cognitive impairment and social function of patients with AD were poorer than elderly patients with depression.