79例铜绿假单胞菌肺炎的临床分析

目的分析铜绿假单胞菌肺炎感染的临床特征、抗牛素敏感性及危险因素等。方法回顾性分析本院2004年发生的铜绿假单胞菌肺炎病例。结果79例患者的临床表现无特异性，大多伴有基础疾病，其中以神经系统疾病最常见。前期使用抗生素、入住ICU和72h内有侵人性操作为感染的主要危险因素。抗生素敏感试验表明，铜绿假单胞菌对阿米卡星、妥布霉索和哌拉西林／他唑巴坦最敏感。结论铜绿假单胞菌肺炎多发生在有各种基础疾病和危险因素的患者，临床表现无特异性，加强耐药性监测和合理应用抗生素十分重要。

Clinical study on 79 cases of Pseudomonas aeruginosa pneumonia

Objective To analyze the clinical characteristics, risk factors of pseudomonas aeruginosa pneumonia and investigate the antibiotic sensitivity of pseudomonas aeruginosa strains. Methods the clinical datd of in - patients with pseudomonas aeruginosa pneumonia were retrospective analyzed, Results The clinical manifestations were nonspecific. Most of the cases had co - existing illness, especially nervous system diseases. Prior antibiotics, care in intensive care unit and invasive procedure within previous 72 hours were the main risk factors. The drug sensitivity test showed that amikacin, tobraw, icin and piperacillin/tazobactam were relatively active against pseudomonas aeruginosa. Conclusion Pseudomonas aeruginosa pneumonia develops in patients with co- existing illness and risk factors, which clinical manifestations are nonspecific. It is very important to select antibiotics correctly according to the results of susceptibility tests.