| 高血压大鼠视网膜组织Ca^2＋酸性磷酸酶组织化学的研究 |
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| 引用本文： | 陈少强.高血压大鼠视网膜组织Ca^2＋酸性磷酸酶组织化学的研究[J].解剖学杂志,1998,21(2):162-166. |
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| 作者姓名： | 陈少强 |
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| 作者单位： | 福建中医学院解剖学教研室!福州350003(喻秉臇)，福建医科大学解剖学教研室(陈少强，陈瑞华，蔡兆明) |
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| 摘 要： | 目的：应用光镜定量酶组织化学方法对正常京都种大鼠（ＷＫＹ）和自发性高血压大鼠（ＳＨＲ）视网膜组织的Ｃａ＾２＋－酸性磷酸酶的分布和活性进行定量观察，结果：Ｃａ＾２＋酸性磷酸酶在ＷＫＹ视网膜组织的活性由强到弱依次为（Ｆ检验，Ｐ〈０．０５）；（１）杆锥细胞内节和外核层；（２）节细胞层；（３）内核层；（４）内网层和外网层；（５）杆锥细胞外节阴性，在ＳＨＲ视网膜组织中，各层Ｃａｓ＾２＋酸性磷酸酶活性下降，以
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| 关 键 词： | 高血压 酸性磷酸酶 组织化学 视网膜病变 |
A STUDY ON ENZYMATIC HISTOCHEMISTRY OF Ca~(2-)-ATP_(asc) IN RETINA OF HYPERTENSIVE RATS |
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| Yu Bingxun,Chen Shaoqiang,Chen Ruihua,Cai Zhaoming.A STUDY ON ENZYMATIC HISTOCHEMISTRY OF Ca~(2-)-ATP_(asc) IN RETINA OF HYPERTENSIVE RATS[J].Chinese Journal of Anatomy,1998,21(2):162-166. |
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| Authors: | Yu Bingxun Chen Shaoqiang Chen Ruihua Cai Zhaoming |
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| Abstract: | To explore the role of Ca2--ATPasc in the retinal damage of spontaneous hypertensive rat (SHR), the distribution of Ca2--ATPasc in the retina of SHR and normal rats (WKY) was observed by quantitative enzymatic histochemistry. The results showed that the intensity sequence of Ca2--ATPasc from high to low in the retina of WKY was inner segment of rod-cone layer and outer nuclear layer, ganglion cell layer, inne nuclear layer, inner plexiform layer and outer plexi-form layer and outer segment of rod-cone layer. The activity of Ca2--ATPasc in the retina of SHR decreased in the inner segment of rod-cone layer, outer nuclear layer and ganglion cell layer. The results suggested that,the decrease of Ca2--ATPasc and calcium overload might be one of the important factors relating to the defect of structures and functions of the retina. |
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| Keywords: | hypertension retina ATPasc histochemistry |
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