Brianodins A-D, briarane-type diterpenoids from soft coral Pachyclavularia sp |
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| Authors: | Ishiyama Haruaki Okubo Taro Yasuda Tetsuro Takahashi Yohei Iguchi Kazuo Kobayashi Jun'ichi |
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| Institution: | Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. |
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| Abstract: | Four new briarane-type diterpenoids, brianodins A-D ( 1- 4), were isolated from a soft coral, Pachyclavularia sp., and the structures and relative stereochemistry of 1- 4 were elucidated on the basis of spectroscopic data. The absolute configurations of 3 and 4 were assigned by the MTPA method. Brianodin A ( 1) showed a modest cytotoxicity. |
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