消糜颗粒治疗HIV／AIDS口腔念珠菌病临床研究

目的:运用消糜颗粒治疗HIV/AIDS口腔念珠菌病,并与制霉菌素片进行对比,研究消糜颗粒治疗HIV/AIDS口腔念珠菌病的疗效及安全性。方法:采用随机平行对照试验的方法。治疗组34例使用消糜颗粒,对照组34例使用制霉菌素片,疗程为1周,使用2个疗程。停药后随访两周。观察指标为临床症状、体征,口腔pH值,同时进行口腔念珠菌培养。结果:病例入选与试验完成情况较好。临床有效性分析,消糜颗粒治疗HIV/AIDS口腔念珠菌病,疗效较好,可以明显改善HIV/AIDS口腔念珠菌病患者临床症状,有效率高。临床安全性分析,治疗期间,个别病人出现消化道症状,继续服药后消失。结论:消糜颗粒治疗HIV/AIDS口腔念珠菌病,可以改善患者临床症状,其有效率可达94.0%,优于制霉菌素片。消糜颗粒治疗HIV/AIDS口腔念珠菌病,复发率低(15.0%),优于制霉菌素片,远期疗效较好。消糜颗粒治疗HIV/AIDS口腔念珠菌病无明显副作用,安全性高。

Clinical Research of Xiaomi Granule on HIV/AIDS Oral Candidiasis

Objective:Observed the clinical effect of Xiaomi granule in HIV/AIDS oral candidiasis treatment in Henan province.Method: Randomly open control study were taked.Thirty four HIV/AIDS oral candidiasis patients were treated with Xiaomi granule for two weeks,and thirty four patients were treated with anticandine tablets as control,clinical syndrome and oral pH were detected,oididmyceties were tested under microscope and were cultivated.Follow-up visit were taked after two weeks.Data were recorded collectedly by...