| Melena： A rare complication of duodenal metastases from primary carcinoma of the lung |
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| 作者姓名： | Kostakou C Khaldi L Flossos A Kapsoritakis AN Potamianos SP |
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| 作者单位： | Department of Gastroenterology University Hospital of Larissa 41447,Greece,Department of Histopathology,University Hospital of Larissa 41447,Greece,Department of Gastroenterology,University Hospital of Larissa 41447,Greece,Department of Gastroenterology,University Hospital of Larissa 41447,Greece,Department of Gastroenterology,University Hospital of Larissa 41447,Greece |
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| 摘 要： | Small bowel metastases from primary carcinoma of the lung are very uncommon and occur usually in patients with terminal stage disease. These metastases are usually asymptomatic, but may present as perforation, obstruction, malabsorption, or hemorrhage. Hemorrhage as a first presentation of small bowel metastases is extremely rare and is related to very poor patient survival. We describe a case of a 61- year old patient with primary adenocarcinoma of the lung, presenting with melena as the first manifestation of small bowel metastasis. Both primary tumor and metastatic lesions were diagnosed almost simultaneously. Upper gastrointestinal endoscopy performed with a colonoscope revealed active bleeding from a metastatic tumor involving the duodenum and the proximal jejunum. Histological examination and immunohistochemical staining of the biopsy specimen strongly supported the diagnosis of metastatic lung adenocarcinoma, suggesting that small bowel metastases from primary carcinoma of the lung occur usually in patients with terminal disease and rarely produce symptoms. Gastrointestinal bleeding from metastatic small intestinal lesions should be included in the differential diagnosis of gastrointestinal blood loss in a patient with a known bronchogenic tumor.
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| 关 键 词： | 原发性肺癌 十二指肠转移 罕见并发症 黑粪症 |
| 收稿时间： | 2006 Dec 12 |
Melena: a rare complication of duodenal metastases from primary carcinoma of the lung |
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| Kostakou C,Khaldi L,Flossos A,Kapsoritakis AN,Potamianos SP.Melena: a rare complication of duodenal metastases from primary carcinoma of the lung[J].World Journal of Gastroenterology,2007,13(8):1282-1285. |
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| Authors: | Kostakou Chrysoula Khaldi Lubna Flossos Andrew Kapsoritakis Andreas N Potamianos Spiros P |
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| Institution: | 1. Department of Gastroenterology, University Hospital of Larissa 41447, Greece
2. Department of Histopathology, University Hospital of Larissa 41447, Greece |
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| Abstract: | Small bowel metastases from primary carcinoma of the lung are very uncommon and occur usually in patients with terminal stage disease. These metastases are usually asymptomatic, but may present as perforation, obstruction, malabsorption, or hemorrhage. Hemorrhage as a first presentation of small bowel metastases is extremely rare and is related to very poor patient survival. We describe a case of a 61- year old patient with primary adenocarcinoma of the lung, presenting with melena as the first manifestation of small bowel metastasis. Both primary tumor and metastatic lesions were diagnosed almost simultaneously. Upper gastrointestinal endoscopy performed with a colonoscope revealed active bleeding from a metastatic tumor involving the duodenum and the proximal jejunum. Histological examination and immunohistochemical staining of the biopsy specimen strongly supported the diagnosis of metastatic lung adenocarcinoma, suggesting that small bowel metastases from primary carcinoma of the lung occur usually in patients with terminal disease and rarely produce symptoms. Gastrointestinal bleeding from metastatic small intestinal lesions should be included in the differential diagnosis of gastrointestinal blood loss in a patient with a known bronchogenic tumor. |
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| Keywords: | Melena Duodenal metastases Lung cancer |
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