| 721例中老年体检者原发性甲状腺功能减退状况调查 |
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| 引用本文： | 杨彬,徐秋梅,柯丽,陈学林,江凌.721例中老年体检者原发性甲状腺功能减退状况调查[J].实用老年医学,2011,25(1):44-46. |
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| 作者姓名： | 杨彬 徐秋梅 柯丽 陈学林 江凌 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院老年科,湖北省武汉市,430022 |
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| 摘 要： | 目的了解目前中老年人群甲状腺功能减退（甲减）的患病率和相应的甲状腺形态学改变。方法参加我院体检的40～79岁的中老年721例为研究对象。电化学发光法检测血清促甲状腺激素（TSH）、游离甲状腺素（FT4）、甲状腺过氧化物酶抗体（A—TPO）和甲状腺球蛋白抗体（A—TG）。全部行甲状腺高灵敏度超声探查。结果筛查出原发性临床甲减患者17例，原发性亚临床甲减患者64例。老年组与中年组临床甲减患病率之比为1．27：1；亚临床甲减患病率之比为2．26：l。其中，老年组女性亚临床甲减患病率较中年组女性患病率明显升高，差异有统计学意义（P〈0．05）；老年组亚临床甲减总患病率高达11．50％，较中年组明显升高（P〈0．05）。甲减患者甲状腺抗体阳性的患病率、临床甲减和亚临床甲减患者甲状腺结节的患病率均较高。结论与中年人群相比，老年人群具有更高的原发性甲减患病率；甲减患者的甲状腺抗体阳性率和甲状腺结节患病率均明显升高。应加强对老年人甲减和甲状腺结节的筛查。
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| 关 键 词： | 甲状腺功能减退 甲状腺结节 老年人 |
Research of the prevalence of primary hypothyroidism in 721 cases of middle and old-aged people |
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| YANG Bin,XU Qiu-mei,KE Li,CHEN Xue-lin,JIANG Ling.Research of the prevalence of primary hypothyroidism in 721 cases of middle and old-aged people[J].Practical Geriatrics,2011,25(1):44-46. |
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| Authors: | YANG Bin XU Qiu-mei KE Li CHEN Xue-lin JIANG Ling |
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| Institution: | YANG Bin,XU Qiu-mei,KE Li,CHEN Xue-lin,JIANG Ling.Department of Geriatrics,Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430022,China |
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| Abstract: | Objective To determine the current prevalence of hypothyroidism in elderly and middle-aged people and to evaluate the morphology of thyroid.Methods 721 cases,aged 40 to 79,were enrolled in this study.Fasting venous blood were collected for detecting serum thyroid stimulating hormone(TSH),free thyroxine(FT4),thyroid peroxidase antibody(A-TPO) and thyroglobulin antibody(A-TG) with electrochemiluminescence assay.Thyroid in every case was screened by high sensitivity ultrasound.Results Seventeen cases with prim... |
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| Keywords: | hypothyroidism thyroid nodules aged |
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