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Intracranial hemorrhage in an infant owing to vitamin K deficiency despite prophylaxis
Authors:K. Suzuki  Takashi Fukushima  Kotoo Meguro  Takeshi Aoki  Takao Kamezaki  Hisako Saitoh  Takao Enomoto  Tadao Nose
Affiliation:(1) Department of Neurosurgery, Tsukuba Medical Center Hospital, Ibaraki, Japan Tel.: +81-297-455111 Fax: +81-297-455050, JP;(2) Department of Pediatrics, Ibaraki Seinan Iryo Center Hospital, Ibaraki, Japan, JP;(3) Department of Pediatrics, Tsukuba Medical Center Hospital, Ibaraki, Japan, JP;(4) Department of Neurosurgery, Ibaraki Seinan Iryo Center Hospital, Ibaraki, Japan, JP;(5) Department of Neurosurgery, University of Tsukuba, Ibaraki, Japan, JP
Abstract:A 3-month-old male infant with intracranial hemorrhage attributable to a vitamin K deficiency is reported. Vitamin K2 was administered orally at birth and then at 5 days and 1 month of age. Oral antibiotics were also given 2 days before the onset of bleeding. Although the incidence of intracranial hemorrhage resulting from vitamin K deficiency has decreased since the introduction of vitamin K2 prophylaxis, spontaneous intracranial hemorrhages are still being reported in infants. We suggest that vitamin K prophylaxis is needed especially for breast-fed infants and for those undergoing antibiotic therapy. Received: 17 January 1998 Revised: 20 January 1999
Keywords:  Intracranial hemorrhage  Vitamin K deficiency  Infant  Prophylaxis
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