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阿立哌唑治疗老年精神分裂症的疗效分析
引用本文:蒋麒麟. 阿立哌唑治疗老年精神分裂症的疗效分析[J]. 中国中医药咨讯, 2010, 2(30): 98-98
作者姓名:蒋麒麟
作者单位:雅安市精神卫生中心,四川,雅安,625000
摘    要:目的探讨阿立哌唑对老年精神分裂症治疗的疗效及安全性。方法采用门诊开放性研究,对42例符CCMD-3精神分裂症或分裂样精神病的老年患者采用阿立哌唑10~20mg/d治疗,评价其有效性和安全性。结果治疗2周后,PANSS阳性、阴性症状分和总分均显著下降(P〈0.05);治疗过程中,无明显体重增加和心血管副反应。结论阿立哌唑能有效缓解老年精神分裂症的精神病性症状,安全性高,适合于老年精神分裂症患者的治疗。

关 键 词:阿立哌唑  精神分裂症  副反应量表

Clinical Stduy of Ariprirazole in the treatment of Schizophrenia with the elderly
Jiang Qi-Lin. Clinical Stduy of Ariprirazole in the treatment of Schizophrenia with the elderly[J]. Journal of China Traditional Chinese Medicine Information, 2010, 2(30): 98-98
Authors:Jiang Qi-Lin
Affiliation:Jiang Qi-Lin
Abstract:Objective To investigate the efficacy and safety of Aripirazole in the treatment of Schizophrenia with the elderly. Methods 42 patients in the study met the diagnostic criterion for Schizophrenia described in the CCMD-3. The dosage of Aripirazole varied from 10mg to 20mg. The efficacy and side effects were ussessed by PANSS, TESSand the changes of biochemical index and electroeardiogram. Results The positive, negative subscores and total score decrease significantly (P 〈 0. 05) after 2 week s' treatment. During the treatment, aecordinh to the TESS averageseoro, 12 patients have never observahle side effects. Conclusion Aripiprazole is safe and effective in the management of psychotic symptoms in old patients with Schizophrenia.
Keywords:Aripiprazole Schizophrenia TESS
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