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Successful Use of Veno-Venous Extracorporeal Membrane Oxygenation in an Adult Patient with Sickle Cell Anemia and Severe Acute Chest Syndrome
Authors:Sarah S. Sewaralthahab  Jay Menaker  Jennie Y. Law
Affiliation:1. Department of Internal Medicine, University of Maryland Medical Center, Baltimore, MD, USA;2. R. Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD, USA;3. Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA
Abstract:A 25-year-old female with sickle cell anemia presented with respiratory failure due to acute chest syndrome (ACS). Given her severely compromised cardiopulmonary status, she was started on veno-venous extracorporeal membrane oxygenation (VV-ECMO). After 20 days, the patient’s respiratory status improved and she was successfully decannulated. Veno-venous extracorporeal membrane oxygenation can be utilized for severe ACS in adult patients with sickle cell disease. Prompt initiation of this modality may improve outcomes in adult patients with sickle cell disease complicated by life threatening ACS.
Keywords:Acute chest syndrome (ACS)  extracorporeal membrane oxygenation (ECMO)  sickle cell disease
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