| 脑出血患者检测血浆ET-1、CGRP的临床意义 |
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| 引用本文： | 刘露,张木坤. 脑出血患者检测血浆ET-1、CGRP的临床意义[J]. 右江民族医学院学报, 2004, 26(2): 169-171 |
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| 作者姓名： | 刘露 张木坤 |
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| 作者单位： | 广东省农垦中心医院检验科,广东,湛江,524002 |
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| 摘 要： | 目的 探讨血浆内皮缩血管肽 1(ET -1)、降钙素基因相关肽 (CGRP)在脑出血患者急性期和恢复期中的临床意义。方法 采用放射免疫分析法 (RIA)对 3 1例脑出血患者急性期和恢复期进行血浆ET -1和CGRP含量测定 ,并与对照组进行比较。结果 脑出血患者急性期血浆ET -1和CGRP含量明显高于对照组 (P均 <0 .0 1) ;恢复期血浆ET-1含量有所下降 ,但仍高于对照组 (P <0 .0 1)。而CGRP在恢复期则降至正常 (P >0 .0 5 )。结论 血浆ET -1、CGRP含量测定对脑损伤程度的判断有重要参考价值。
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| 关 键 词： | 脑出血 内皮素 降钙素基因相关肽 实验室检查 |
| 文章编号： | 1001-5817(2004)02-0169-03 |
| 修稿时间： | 2003-12-23 |
The clinical significance of ET-1 and CGRP in cerebral hemorrhage |
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| LIU Lu,ZHANG Mu-kun. The clinical significance of ET-1 and CGRP in cerebral hemorrhage[J]. Journal of Youjiang Medical College For Nationalities, 2004, 26(2): 169-171 |
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| Authors: | LIU Lu ZHANG Mu-kun |
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| Abstract: | Objective To study the clinical significance of blood plasma endothelin-1 (ET-1) and calcitonin gene-related peptide (CGRP) in acute and convalescence periods in patients with cerebral hemorrhage. Methods A radioimmunoassay(RIA) method was used to detect the ET-1 and CGRP in the acute and convalescence periods in patients with cerebral hemorrhage. Then a comparison to the control group was also untaken. Results The ET-1 and CGRP in the acute period of cerebral hemorrhage were statistically higher than that in the control group (all the P values were <0.01); in the convalescence period, the blood plasma ET-1 decreased slightly. but still higher than that in the control group (P<0.01). The CGRP decreased to a normal level in the convalescence period (P>0.05). Conclusion Blood plasma ET-1 and CGRP are useful markers for diagnosis of cerebral injury. |
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| Keywords: | cerebral hemorrhage endothelin-1 calcitonin gene-related peptide laboratory examination |
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