Reorganization of human cortical maps caused by inherited photoreceptor abnormalities |
| |
Authors: | Baseler Heidi A Brewer Alyssa A Sharpe Lindsay T Morland Antony B Jägle Herbert Wandell Brian A |
| |
Affiliation: | Department of Psychology, Stanford University, Stanford, California, USA. |
| |
Abstract: | We describe a compelling demonstration of large-scale developmental reorganization in the human visual pathways. The developmental reorganization was observed in rod monochromats, a rare group of congenitally colorblind individuals who virtually lack cone photoreceptor function. Normal controls had a cortical region, spanning several square centimeters, that responded to signals initiated in the all-cone foveola but was inactive under rod viewing conditions; in rod monochromats this cortical region responded powerfully to rod-initiated signals. The measurements trace a causal pathway that begins with a genetic anomaly that directly influences sensory cells and ultimately results in a substantial central reorganization. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|