尿路感染患者分离的202株大肠埃希菌的耐药性检测

目的]了解尿路感染患者大肠埃希菌的产ESBLs检测和耐药情况。方法]2008年6月至2010年6月从尿路感染住院患者的尿液标本中分离的202株大肠埃希菌,采用ATB细菌鉴定分析仪进行产ESBLs检测和药敏试验。结果]202株大肠埃希菌中检出产ESBLs菌81株,占40.09%;非产ESBLs菌121株,占59.91%。产ESBLs菌的耐药率为70.37%（57/81）,非产ESBLs菌的耐药率为26.45%（32/121）,差异有统计学意义（P〈0.01）。结论]大肠埃希菌产ESBLs株耐药性强,应结合药敏试验选择合适的药物。

Test of Drug Resistance of 202 Escherichia Coli Strains Isolated from Urinary Tract Infection Patients

Objective] To understand the detection of ESBLs producing Escherichia coli and drug resistance in urinary tract infection patients.Methods]Examination of ESBLs and drug sensitivity was conducted with ATB bacilli analyzer for 202 Escherichia coli strains isolated from inpatients with urinary tract infection from June 2008 to June 2010.Results]Of the 202 Escherichia coli strains,81 ESBLs producing stains were detected,accounting for 40.09%,121 non-ESBLs producing stains,accounting for 59.91%.Drug resistant rate of ESBLs producing stains was 70.37%（57/81） and non-ESBLs producing stains was 26.45%（32/121）.There was a difference（P0.01）.Conclusion]ESBLs producing Escherichia coli stains had strong drug resistance.Antibiotics should be used rationally based on drug sensitivity test.