Variably Acid-fast Bacteria in a Rare Case of Coexistent Malignant Lymphoma and Cutaneous Sarcoid-like Granulomas |
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| Authors: | Alan R Cantwell JR MD |
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| Institution: | From the Department of Dermatology, Southern California Permanente Medical Croup and Kaiser Foundation Hospital, Los Angeles, California |
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| Abstract: | ABSTRACT: A 74-year-old woman presented clinical, laboratory, and histologic evidence of coexistent cutaneous sarcoid-like granulomas, malignant lymphocytic lymphoma, and multiple basal cell carcinomas, all occurring within slightly more than a one-year period. Variably acid-fast coccoid forms were observed in the histologic sections of the cutaneous, non-caseating granulomas: and similar, variably acid-fast, extra and intracelluar coccoid forms and granular bodies were seen in the lymph nodes showing lymphoma. The possible relationship between sarcoid-like granulomas, sarcoidosis, and malignancy is discussed, as well as the possible role of cell wall deficient forms (L-forms) of mycobacteria in the pathogenesis of these diseases. |
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