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Clinical efficacy and safety of CPT-11+CDDP therapy as third-line chemotherapy for advanced and recurrent gastric cancer
Authors:Godai Ten I  Oshima Takashi  Numata Masakatsu  Fukahori Michiko  Sato Tsutomu  Makino Hirochika  Fujii Shoichi  Rino Yasushi  Masuda Munetaka  Imada Toshio  Kunisaki Chikara
Affiliation:Dept. of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama City University.
Abstract:The clinical efficacy and safety of CPT-11+CDDP therapy were studied retrospectively in 34 patients with advanced and recurrent gastric cancer. The overall response rate was 5. 9%; MST was 209 days. The adverse effects observed were grade 3 in 7 patients(20. 6%). CPT-11+CDDP therapy could be useful and safe as third-line chemotherapy.
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