阳和汤配合介入治疗在下肢动脉硬化闭塞症中的应用

目的:探讨阳和汤配合介入治疗对下肢动脉硬化闭塞症的临床价值。方法:34例下肢动脉硬化闭塞症患者随机分为治疗组(17例)和对照组(17例),对照组给予基础治疗和介入治疗,治疗组在对照组治疗方案基础上加用阳和汤口服;治疗时间均为介入术后3个月;2组于治疗前及治疗后3个月测踝肱指数(ankle/brachial index,ABI),治疗后3个月随访2组临床症状体征改善情况,并比较有效率。结果:与治疗前相比,介入治疗后3个月2组ABI均明显增加,差异均有统计学意义(P0.05);治疗组增加程度明显高于对照组,差异有统计学意义(P0.05)。治疗后3个月2组间治疗有效率及间歇性跛行、静息痛治疗有效率差异无统计学意义(P0.05)。治疗组皮肤苍白、皮肤温度改善程度优于对照组,差异有统计学意义(P0.05)。结论:阳和汤可增加下肢动脉硬化闭塞症介入治疗术后ABI,改善临床症状体征,是介入治疗下肢动脉硬化闭塞症的有力补充。

Application of traditional Chinese medicine YangheTang combined with interventional treatment for lower limb arteriosclerosis obliterans

Objective：To discuss the clinical value of traditional Chinese medicine YangheTang combined with interventional therapy on lower limb arteriosclerosis obliterans. Methods：Thirty-four patients with lower limb arteriosclerosis obliterans were assigned randomly to two groups, the control group and the treatment group, both were treated with basic and interventional therapy,but YangheTang were given to the treatment group for 3 months additionally. ABI was measured 3 months before and after treatment,moreover,the total efficiency and the clinical symptom improvement rate were determined in the 3-month follow-up studies. Results：Significant improvements of ABI were shown in both groups after treatment in comparing with it before treatment（P〈0.05）,and the treatment group was higher （P〈0.05）. Comparisons between groups after 3-month treatment showed similar in the total efficiency and effective rate of intermittent claudication and rest pain treatment （P〈0.05）. Comparing the control group, the treatment group was better in improvement of skin color and skin temperature after 3-month treatment （P〈0.05）. Conclusions： YangheTang is a strong supplement of interventional therapy, because it could improve ABI and the clinical symptoms in patients with lower limb arteriosclerosis obliterans.