CT和MRI小肠造影对克罗恩病活动期和静止期的对照研究

目的:探讨CT和MRI小肠造影对克罗恩病(Crohn’s disease,CD)活动期与静止期的诊断价值。方法:回顾性分析经手术病理证实的72例CD患者的CT和MRI小肠造影表现,重点观察病变活动期及静止期情况。结果:72例CD中,病变活动期48例,静止期24例。活动期指标:肠壁分层增厚(36/48)、黏膜中重度强化(42/48)、肠壁溃疡形成(14/48)、肠腔狭窄(22/48)、肠瘘(11/48)、蜂窝织炎(13/48)、淋巴结肿大(18/48)、木梳征象(10/48),以上8种征象与静止期比较差异均有统计学意义(P0.05)。静止期指标:肠壁单层增厚(16/24)、黏膜不强化或轻度强化(19/24)、息肉形成(12/24)、腹腔脓肿(6/24),以上4种征象与活动期比较差异均有统计学意义(P0.05)。结论:CT和MRI小肠造影可全面评价CD的活动期与静止期表现,对于指导CD的临床治疗具有重要价值。

Comparative study of CT and MRI enterography in activity and quiescence for Crohn disease

Objective：To investigate the CT and MRI enterography in activity and quiescence for Crohn disease （CD）. Methods： 72 patients with CD were confirmed by surgery and pathology. The CT and MRI enterography imaging performance were analyzed retrospectively, with a focus on the activity and the quiescence. Results： Among the 72 cases of CD, 48 cases were in activity and the other 24 cases were in quiescence. The activity indicators included： multi-layer thickening of bowel wall （36/48）, moderate or severe mucosal enhancement （42/48）, ulcer in intestinal wall （14/48）, the lumen stenosis （22/48）, intestinal fistula （11/48）, cellulitis （13/48）, lymph node enlargement （18/48）, wooden comb sign （10/48）. The above eight kinds of signs had statistical significance difference compared with chronic phase （ P 〈 0.05）. Chronic phase indicators： single-layer thickening of bowel wall （16/24）, no or mild enhancement （19/24）, the formation of polyps （12/24）, abdominal abscess （6/ 24）. Four kinds of signs were statistically significant compared with active phase （ P 〈0.05）. Conclusion：CT and MRI enterography can be comprehensive evaluation to CD in activity and quiescence, and it has important value in guiding the clinical treatment.