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半张液细菌内毒素检查法的研究
引用本文:王雪瓶,于永菊,周文.半张液细菌内毒素检查法的研究[J].中国医院药学杂志,1999,19(10):605-606.
作者姓名:王雪瓶  于永菊  周文
作者单位:山东医科大学附属医院!济南,250012,山东医科大学附属医院!济南,250012,山东医科大学附属医院!济南,250012,山东医科大学附属医院!济南,250012,山东医科大学附属医院!济南,250012
摘    要:研究半张注射液(半张液)细菌内毒素检查(BET)的干扰试验,以便建立用BET代替热原检查(PT)。方法:按1995年版中国药典附录76页“细菌内毒素检查法”操作。结果:样品采用灵敏度0.25EU·ml-1的鲎试剂或特异性鲎试剂经干扰试验无抑制增强作用。结论:本实验具有准确性,可靠性,适合半张液的检查。

关 键 词:鲎试剂  特异性鲎试剂  细菌内毒素  干扰试验

The study of the bacteria endotoxin test for glucose (5%) and sodium chloride(O.45%) injection
Wang Xueping, Yu Yongiu, Zhou Wen, et al.The study of the bacteria endotoxin test for glucose (5%) and sodium chloride(O.45%) injection[J].Chinese Journal of Hospital Pharmacy,1999,19(10):605-606.
Authors:Wang Xueping  Yu Yongiu  Zhou Wen  
Abstract:To establish a methed for Bacteria Endotoxin Test(BET) instead of the Pyrogen Test(PT) through thestudy of BET for glucose(5%) and wsodium chloride (o. 45%) injection. METHODS: Acoording the methed of BET appendix page76, the pharmacopoeia of china (1995). RESULTS: Using sensitivity o. 25 EU' ml-1 tachypleus ameboyte lysate for endotoxin detection or tachypleus ameboyte lysate ES-Test for interfere test, there is no inhibition or enhancement action. CONCLUSTIONS: Themethed is accurate and believable and suitable for the BET of glucase(5%) and whiurn chloride (o. 45 % ) injection.
Keywords:tachypleus amebocyte lysate  tachypleus amebocyte lysate ES-Test  bacteria endotoxin  interfere test  
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