3种中药重金属成分铅、镉的含量分析

目的:了解市售中药中重金属含量情况,并分析导致中药中重金属含量超标的可能因素。方法:随机抽取市售中药元胡止痛片、制草乌、藿香共9个样品,按照2005年版《中国药典》(一部)附录重金属检查法中有关铅、镉的含量测定法进行实验。结果:3种中药共9个样品中铅、镉的含量除藿香全部合格外,其它各有不同程度的超标。结论:市售中药中铅、镉含量的超标现象较普遍,这与药品的生产工艺、炮制工艺、产地环境等因素密切相关,并已成为导致某些中药不良反应的原因之一。

Content Analysis of Heavy Metal Ingredients Pb,Cd in Three Traditional Chinese Medicines

OBJECTIVE: To investigate the contents of heavy metal ingredients( Pb, Cd) in three traditional Chinese medicines and analyze the possible factors which cause the content of heavy metals being higher than the criterion. METHODS: 9 samples of 3 marketed Chinese medicines-Yuanhuzhitong tablets, radix aconite kusnezoffii preparata and herba pogostemonis-were randomly chosen. The assaying of Pb, Cd was conducted in accordance with the Appendix on determination of heavy metal contents in Chinese Pharmacopoeia ( Volume 1) of 2005 edition. RESULTS: Among the 9 samples of the 3 medicines, the contents of Pb, Cd exceeded the criterion to different extents except in herba pogostemonis. CONCLUSIONS: It is common that the contents of heavy metal ingredients in marketed traditional Chinese medicines exceed the standard. This is closely associated with the production technique, processing technique and environment of place of origin, and has become one of the causes for adverse reactions in certain Chinese medicines.