|
|||||
|
|
| 脂蛋白相关磷脂酶A2与急性缺血性脑卒中的相关性研究 | |
| 引用本文： | 金艳,张春和,刘景霞,肖国辉.脂蛋白相关磷脂酶A2与急性缺血性脑卒中的相关性研究[J].国际检验医学杂志,2012,33(1):29-30. |
| 作者姓名： | 金艳 张春和 刘景霞 肖国辉 |
| 作者单位： | 1. 河北省沧州市人民医院检验科,061000 2. 河北省沧州市第三医院检验科,061001 3. 河北省沧州市南皮县医院检验科,061500 |
| 摘 要： | 目的 通过检测急性缺血性脑卒中患者血浆脂蛋白相关磷脂酶A2(Lp-PLA2)浓度,探讨两者的关系,为临床诊断、治疗提供依据.方法 选择急性缺血性脑卒中患者(151例)为研究对象,未卒中患者(100例)作对照,血浆Lp-PLA2检测采用酶联免疫吸附法(ELISA).结果 (1)急性缺血性脑卒中组血浆Lp-PLA2浓度高于对照组,差异有统计学意义(t=21.307,P=0.000).血浆Lp-PLA2浓度与急性缺血性脑卒中的风险呈正相关.(2)各型急性缺血性脑卒中血浆Lp-PLA2浓度差异均无统计学意义(P＞0.05).结论 Lp-PLA2是急性缺血性脑卒中的危险标志物,测定Lp-PLA2浓度有助于制定预防策略,为急性缺血性脑卒中的预防及临床治疗提供依据. |
| 关 键 词： | 卒中 脂蛋白相关磷脂酶A2 相关性 |
Correlation study about lipoprotein associated lipoprotein phospholipase A2 and acute ischemic strokes |
|
| Jin Yan,Zhang Chunhe,Liu Jingxia,Xiao Guohui.Correlation study about lipoprotein associated lipoprotein phospholipase A2 and acute ischemic strokes[J].International Journal of Laboratory Medicine,2012,33(1):29-30. | |
| Authors: | Jin Yan Zhang Chunhe Liu Jingxia Xiao Guohui |
| Institution: | 1.Department of Laboratory,People′s Hospital of Cangzhou,Cangzhou,Hebei 061000,China; 2.Department of Laboratory,Third Hospital of Cangzhou,Cangzhou,Hebei 061001,China; 3.Department of Laboratory,Nanpi County Hospital,Cangzhou,Hebei 061500,China) |
| Abstract: | Objective To explore the relationship between plasma level of lipoprotein associated phospholipase A2(Lp-PLA2) and acute cerebral arterial thrombosis(ACAT) to provide the basis for clinical diagnosis and therapy of disease.Methods Enzyme-linked immunosorbent assay(ELISA) was performed for the detection of plasma level of Lp-PLA2 in 151 cases of patients with ACAT (experimental group) and 100 cases of healthy controls(control group).Results (1) Plasma level of Lp-PLA2 in experimental group were higher than control group(t=21.307,P=0.000).There were positive correlations between plasma Lp-PLA2 level and the risks factors of ACAT.(2)There was no difference of plasma Lp-PLA2 level between patients with different types of ACAT (P>0.05).Conclusion Lp-PLA2 could be a risk marker for ACAT and detection of its plasma level might be helpful for guiding prevention strategies and providing basis for clinical therapy. |
| Keywords: | stroke lipoprotein associated phospholipase A2 relevance |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |