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自体MSC-NSCs治疗小儿急性播散性脑脊髓炎后瘫痪1例
引用本文:王亚莉,陈国军,方凤,陈丽,刘厚奇. 自体MSC-NSCs治疗小儿急性播散性脑脊髓炎后瘫痪1例[J]. 免疫学杂志, 2012, 0(8): 730-731,736
作者姓名:王亚莉  陈国军  方凤  陈丽  刘厚奇
作者单位:浙江武警总队医院;第二军医大学发育生物学研究所
基金项目:国家重点基础研究发展计划(2011CB965101)
摘    要:目的观察自体骨髓间充质干细胞转化神经干细胞移植对急性播散性脑脊髓炎后下肢瘫痪的治疗效果。方法采集自体骨髓分离间充质干细胞体外培养增殖后诱导为神经干细胞后移植给患儿。结果患儿下肢的功能明显恢复。结论自体骨髓间充质干细胞转化神经干细胞移植是急性播散性脑脊髓炎后下肢瘫痪的有效方法。

关 键 词:骨髓间充质干细胞  神经干细胞  急性播散性脑脊髓炎  瘫痪

Efficacy of autologous MSC-NSCs treatment on the paralysis occurred after acute disseminated encephalomyelitis in child: a case report
WANG Yali,CHEN Guojun,FANG Feng,CHEN Li,LIU Houqi. Efficacy of autologous MSC-NSCs treatment on the paralysis occurred after acute disseminated encephalomyelitis in child: a case report[J]. Immunological Journal, 2012, 0(8): 730-731,736
Authors:WANG Yali  CHEN Guojun  FANG Feng  CHEN Li  LIU Houqi
Affiliation:Zhejiang Armed Police Hospital,Jiaxing 314000,China
Abstract:We reported a case of child with lower limbs paralysis caused by acute disseminated encephalomyelitis after vaccination.The child had treated with transplantation of neural stem cell derived from autologous bone marrow mesenchymal stem cells.After the treatment,we found the lower limbs function of the child was obviously recovered.The autologous MSC-NSCs transplantation is an effective therapy to lower limb paralysis after acute disseminated encephalomyelitis.
Keywords:Bone marrow-derived mesenchymal stem cells  Neural stem cells  Acute disseminated encephalomyelitis  Paralysis
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