| TGF-β在骨折愈合中的调控 |
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| 引用本文： | 周燕,张纲,卓贤露,谭颖徽. TGF-β在骨折愈合中的调控[J]. 免疫学杂志, 2012, 0(4): 353-355,362 |
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| 作者姓名： | 周燕 张纲 卓贤露 谭颖徽 |
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| 作者单位： | 第三军医大学新桥医院口腔科 |
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| 摘 要： | TGF-β(转化生长因子-β)是一种多功能细胞因子,在骨折愈合过程中,TGF-β对细胞增殖、分化以及细胞外基质合成起重要调节作用。从修复开始到骨形成的不同阶段中都有TGF-β的定位及表达。目前研究TGF-β在骨折愈合方面的应用前景广阔。随着组织工程学的深入研究,骨折愈合这个临床上的难题有望得到突破,本文就相关方面的研究做一综述。
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| 关 键 词： | 转化生长因子 骨折愈合 调控 |
Regulation of TGF-beta in fracture healing |
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| ZHOU Yan,ZHANG Gang,ZHUO Xianlu,TAN Yinghui. Regulation of TGF-beta in fracture healing[J]. Immunological Journal, 2012, 0(4): 353-355,362 |
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| Authors: | ZHOU Yan ZHANG Gang ZHUO Xianlu TAN Yinghui |
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| Affiliation: | Department of Stomatology,Xinqiao Hospital,Third Military Medical University,Chongqing 400037,China |
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| Abstract: | Transformation growth factor-beta(TGF-β) is a kind of multi-functional cell factor.In the fracture healing process,TGF-β weeping,differentiation and extracellular matrix synthesis play an important regulatory role on cell growth.TGF-β is found in different stages of bone repair.The present study reveal broad prospect for application of TGF-beta in fracture healing.With the development of tissue engineering,problems in fracture healing is expected to be conquered,and this review summarizes the related research in this field. |
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| Keywords: | TGF-β Fracture healing Regulation |
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