Case of primary localized cutaneous amyloidosis with protean clinical manifestations: lichen, poikiloderma-like, dyschromic and bullous variants |
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Authors: | Chandran Nisha Suyien Goh Boon-Kee Lee Siong-See Goh Chee-Leok |
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Institution: | National Skin Centre, Singapore, Singapore. nishasuch@gmail.com |
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Abstract: | Primary localized cutaneous amyloidosis (PLCA) commonly presents as macular and lichen variants. We present a case of a 27-year-old Chinese woman with cutaneous features of the rarely reported poikiloderma-like, dyschromic and bullous forms of PLCA, and the commoner lichen variant. There were no syndromic associations or systemic involvement, and the various morphological subtypes occurred in isolation from one another. We review the clinical spectrum of PLCA, highlight its protean clinical manifestations in this patient, and discuss its postulated pathogenesis in relation to its histopathological features. |
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Keywords: | amyloidosis cutis dyschromica bullous amyloidosis dyschromia lichen amyloidosis poikiloderma |
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