Author index volume 15 (1980) |
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Authors: | O. Meyer E. Hansen |
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Affiliation: | National Food Institute, Institute of Toxicology, 19, Mørkhøj Bygade, DK 2860 Søborg, Copenhagen, Denmark |
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Abstract: | Butylated hydroxytoluene (BHT) 500 mg/kg body wt/day was given in the diet to F0-rats from 6 weeks of age to weaning of the F1-generation (growth period to age 19 week, gestation period and lactation period) and subsequent to F1-animals until 21 days of age. Body weight of F0-animals was recorded, and the influence of the F1-generation was investigated applying crossfostering. Mortality, litter size, weight gain and some developmental events as well as test for auditory and visual function and locomotor coordination in the F1-generation were recorded.The applied dose of BHT exerted a significant adverse effect on body weight in both F0 and F1-animals and on several developmental paramenters in F1-animals. The effects arose during the lactation period. |
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Keywords: | BHT butylated hydroxytoluene |
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