| 心肌挫伤后心肌酶谱和心脏肌钙蛋白-T的含量变化 |
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| 引用本文： | 闵家新,朱佩芳,王正国,刘宝松,翁格文.心肌挫伤后心肌酶谱和心脏肌钙蛋白-T的含量变化[J].第三军医大学学报,2000,22(2):139-141. |
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| 作者姓名： | 闵家新 朱佩芳 王正国 刘宝松 翁格文 |
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| 作者单位： | 第三军医大学附属大坪医院野战外科研究所第四研究室,重庆,400042 |
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| 基金项目： | 国家自然科学基金!(39630330) |
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| 摘 要： | 目的：观察心脏肌钙蛋白－Ｔ（ｃＴｎ－Ｔ）和心肌酶谱（ＭＥ）在心肌挫伤（ＣＣ）后含量变化及其对ＣＣ的诊断价值。方法：采用兔钝性胸部创伤（ＢＣＴ）模型，致成中度至重度ＣＣ，分别在伤前、伤后４、８和２４ｈ抽箅测定血清ｃＴｎ－Ｔ和ＭＥ含量。结果：伤后４ｈ，血精ｃＴｎ－Ｔ和ＭＥ含量明显升高（Ｐ〈０．０１），持续至伤后２４ｈ。其中ｃＴｎ－Ｔ在伤后２４ｈ升高最为明显，ＭＥ有下降，但仍然明显高于伤前（Ｐ〈０．０１
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| 关 键 词： | 心肌挫伤 心脏肌钙蛋白－T 心肌酶谱 |
Experimental study of comparison of diagnosis of cardiac contusion in rabbits |
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| MIN Jia-xin,ZHU Pei-fang,WANG Zheng-guo,LIU Bao-song,WENG Ge-wen.Experimental study of comparison of diagnosis of cardiac contusion in rabbits[J].Acta Academiae Medicinae Militaris Tertiae,2000,22(2):139-141. |
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| Authors: | MIN Jia-xin ZHU Pei-fang WANG Zheng-guo LIU Bao-song WENG Ge-wen |
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| Institution: | MIN Jia-xin, ZHU Pei-fang, WANG
Zheng-guo, LIU Bao-song,WENG Ge-wen
(Research Institute of Field Surgery, Daping Hospital, Third Military Medical University,
Chongqing 400042) |
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| Abstract: | Objective: To observe the changes of the cardiac troponin T (cTn T) and myocardial enzyme (ME) in plasma and to assess their value in diagnosis of cardiac contusion (CC) after blunt chest trauma (BCT). Methods: Before and at the 4th, 8th and 24th h after the model of BCT was established in rabbits, the cTn T and ME contents were determined. Results: The contents of cTn T and ME were remarkably increased from the 4th to 24th h after BCT (P<0.01). The content of cTn T reached its peak while that of ME was slightly decreased at the 24th h after BCT. The latter was still significantly higher than that before the trauma (P<0.01). Conclusion: It is helpful for diagnosis of CC after BCT to measure the changes of cTn T and ME contents in plasma. CTn T is more sensitive than ME in diagnosis of CC after BCT. |
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| Keywords: | cardiac contusion troponin T myocardial enzyme blunt chest trauma |
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