基于CiteSpace知识网络图谱的黄芩研究进展

目的 分析2000—2020年已发表的黄芩相关的国内外文献，发现研究热点和发展趋势，为今后研究提供参考。方法 检索中国知网(CNKI)及Web of Science，运用文献计量学及CiteSpace 5.8.R3软件对研究作者、研究机构及关键词等内容进行可视化展示，并结合信息提取的方法对黄芩研究现状及发展趋势进行分析。结果 《中国实验方剂学杂志》《Journal of Ethnopharmacology》分别是发表中文和英文文献最多的期刊；杜明、Qinglong Guo分别是发表中文和英文文献最多的作者；发文机构分析显示中国中医科学院中药研究所、China Pharmaceutical University是发表中文和英文文献最多的研究机构；中、英文文献关键词分析显示黄芩研究主要集中在代谢组学、化学成分、药理作用、药动学、作用机制和胰岛素抵抗。结论 机制研究、药动学和胰岛素抵抗可能是黄芩今后的研究热点。目前黄芩相关的研究仍处于发展阶段，需注重研究的深入并加强作者或机构的合作。

Research Progress of Scutellaria Baicalensis Based on CiteSpace Knowledge Network Map

OBJECTIVE To find the research hotspots and development trends and provide foreshadowing and reference for future research,the domestic and foreign literatures related to Scutellaria baicalensis published from 2000 to 2020 were analyzed. METHODS By searching CNKI and Web of Science,using bibliometrics and CiteSpace 5.8.R3 software to visually display the research authors,research institutions and keywords,and combined with the method of information extraction to analyze the research status and development trend of Scutellaria baicalensis.RESULTS Chinese Journal of Experimental Traditional Medical Formulae and Journal of Ethnopharmacology were the most published journals in Chinese and English respectively;Du Ming and Qinglong Guo were the most published authors in Chinese and English respectively;The analysis of issuing institutions showed that the institute of Traditional Chinese Medicine of the Chinese Academy of Traditional Chinese Medicine and China Pharmaceutical University were the research institutions that published the most Chinese and English documents;Keyword analysis of Chinese and English literature showed that the research of Scutellaria baicalensis mainly focuse on metabolomics,chemical composition,pharmacological effects,pharmacokinetics,mechanism of action and insulin resistance.CONCLUSION Mechanism research,pharmacokinetics and insulin resistance may be the research focus of Scutellaria baicalensis in the future.At present,research on Scutellaria baicalensis is still in the development stage,and it is necessary to focus on the in-depth research and strengthen the cooperation of authors or institutions.