不同年龄和心率3460例健康人二尖瓣多普勒血流频谱分析

目的　探讨生理性舒张功能减退与早期舒张性心力衰竭的鉴别依据。方法　应用多普勒超声心动图观察 3 460例不同年龄和心率健康人的二尖瓣血流频谱 ,其中男 14 13例 ,女 2 0 47例 ,年龄 16～ 97岁 ,按年龄分为 16～、3 0～、40～、5 0～、60～、>70岁共 6组 ,每组再根据心率分为 5 0～、60～、70～、80～、90～次 /分共 5组。结果　随年龄增长 ,舒张早期血流 (E波 )的峰值流速 (EPFV)减慢 (P =0 .0 0 0 <0 .0 1) ;心房收缩期血流 (A波 )的峰值流速 (APFV)加快 (P =0 .0 0 0 <0 .0 1) ,E/A比值下降 (P =0 .0 0 0 <0 .0 1)。随心率加快 ,心房收缩期血流 (A波 )的峰值流速 (APFV)加快 (P =0 .0 0 0 <0 .0 1) ,E/A比值下降 (P =0 .0 0 0 <0 .0 1)。建立年龄和心率综合分析的量表。结论　年龄和心率是影响左室舒张功能的重要因素 ,在诊断早期舒张性心力衰竭时必须予以考虑。

Analysis of Mitral Valve Blood Flow Velocity in Early and Late Diastole in 3460 He alth Subjects by Pulsed Doppler Echocardiography

Objective To investigate the differences between decreased left ventricular diastolic function and diastolic heart failure in early stage. Methods Doppler echocardiography was performed in 3460 healthy subjects with different heart rate and age.The subjects were divided into 16-, 30-, 40-, 50-, 60-, >70 six age groups according to their age,and 50- , 60-, 70-, 80-, 90- five groups according to their heart rates. Results With increasing age,peak flow velocity of early diastole (EPFV) decreased and peak flow velocity of atrial contraction (APFV) increased ( P =0.000<0.01). With increasing heart rate,peak flow velocity of early diastole (EPFV) decreased ( P =0.000<0.01) but peak flow velocity of atrial contraction (APFV) did not change. Whether increasing age or increasing heart rate,the ratio between EPFV and APFV all significantly decreased( P =0.000<0.01). General analysis data criteria had been established. Conclusion Age and heart rate are important factors in influencing left ventricular diastolic function. It must be considered when we diagnose diastolic heart failure in early stage.