| 蒺藜皂苷对高脂血症的影响 |
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| 引用本文： | 褚书地,瞿伟菁,逄秀凤,孙斌,黄晓青. 蒺藜皂苷对高脂血症的影响[J]. 中药材, 2003, 26(5): 341-344 |
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| 作者姓名： | 褚书地 瞿伟菁 逄秀凤 孙斌 黄晓青 |
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| 作者单位： | 华东师范大学生命科学学院,上海,200062 |
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| 摘 要： | 以高脂饲料诱导高脂血症小鼠模型，研究了蒺藜皂苷的调血脂作用。研究表明：蒺藜皂苷能降低实验性高脂血症小鼠血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)及肝脏胆固醇、甘油三酯的含量；在灌胃蒺藜皂苷的同时继续喂食高脂饲料，能有效地阻止血清胆固醇、低密度脂蛋白胆固醇(LDL-C)的升高，同时能降低肝脏胆固醇、甘油三酯的含量，提高肝脏超氧化物歧化酶的(SOD)的活性。
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| 关 键 词： | 蒺黎皂苷 高脂血症 甘油三酪 低密度脂蛋白胆固醇 胆固醇 小鼠 实验研究 |
| 修稿时间： | 2002-11-29 |
Effect of Saponin from Tribulus terrestris on Hyperlipidemia |
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| Chu Shudi,Qu Weijing,Pang Xiufeng,Sun Bin,Huang Xiaoqing. Effect of Saponin from Tribulus terrestris on Hyperlipidemia[J]. Journal of Chinese medicinal materials, 2003, 26(5): 341-344 |
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| Authors: | Chu Shudi Qu Weijing Pang Xiufeng Sun Bin Huang Xiaoqing |
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| Affiliation: | School of Life Science, East China Normal University, Shanghai 200062. |
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| Abstract: | The preventive and therapeutic effects of saponin from Tribulus terrestris L. on diet-induced hyperlipidemia in mice have been studied. It showed that in preventive experiment the saponin could significantly low the levels of serum TC (P < 0. 05 ) , LDL-c ( P < 0. 01) and liver TC ( P < 0. 05 ) , TG ( P < 0. 05 ) , and increase the activities of superoxide-dismutase ( SOD ) in liver. The therapeutic experiment showed that the saponin could significantly reduce the contents of serum TC ( P < 0. 05 ) and liver TC |
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| Keywords: | Tribulus terrestris Hyperlipidemia Triglyceride Cholesterol Low density lipoprotein-cholesterol (LDL-C) Super-oxide-dismutase (SOD) |
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