Pharmakotherapie der weiblichen Harninkontinenz

Stress urinary incontinence of women is especially in the middle age the most frequent incontinence form and causes considerable psychological strain. Up to now there was no effective pharmacological therapy for stress urinary incontinence. Since 2004 the dual working serotonin-noradrenaline reuptake inhibitor Duloxetin is available. Conservative and pharmacological therapies, especially in combination, cause a relative time preliminary before frequent too early operations. The overactive bladder syndrome with or without incontinence generates enormously high psychological strain, because the controlling loss of the bladder degradates the patients on the level of childhood. The big offer of anticholinergics facilitate an individual patient’s care to the expert doctor. The therapy of the overactive bladder syndrome limited itself long time to the clinical application of so-called “classic anticholinergics”. The long term compliance of the treated patients was only moderate because either side effects were not tolerated, or the effectiveness was insufficient. New application forms, receptor selectivity, pharmacokinetic and the improvement of side effect profile allow an individual therapy and improve patient satisfaction and compliance.