四川遂宁地区表观健康老年人群血细胞分析参考区间的适宜性验证

目的 验证《中国老年健康人群血常规检测结果多中心调查》文中表7提供的中国老年健康人群血细胞分析参考区间是否适用于遂宁地区的表观健康老年人群.方法 参照行业标准WS/T402-2012、WS/T405-2012及其他文献制定纳入标准及排除标准,从遂宁市中心医院体检人群中共募集1023例60～79岁的老年表观健康个体,按性...

A Verification of the Suitability of Reference Interval for Blood Cell Analysis in an Apparently Healthy Elderly Population in Suining,Sichuan

Objective To verify whether the reference range of blood cell analysis in Chinese healthy elderly population provided in Table 7 from the Multicenter Survey of Blood Routine Examination in Apparently Healthy Elderly Population in China is applicable to the apparently healthy elderly population in Suining.Methods According to industry standards WS/T402-2012,WS/T405-2012 and other literatures,the inclusion and exclusion criteria were formulated.1,023 apparently healthy elderly individuals aged from 60 to 79 years were divided into 4 groups according to gender and age.We analyzed whether the ratio(coincidence rate)of blood cell analysis test results in each group falling within the reference interval was≥90%,in which case,the verification in the reference interval was considered to be passed.When the coincidence rate failed to pass or the reference interval was not provided,the reference interval was established by a non-parametric method.Results The results of related parameters of red blood cells and white blood cells in each group were more than 90%within the reference range provided in Table 7 of the Multicenter Survey on Blood Routine Test Results of Healthy Elderly People in China,and the reference interval was verified.However,the platelet count(PLT)of men aged of 70 to 79 years old was only 83.41%within the reference range,which failed to pass the verification reference range.Through analysis,we obtained the red blood cell volume distribution width-coefficient of variation(RDW-CV),red blood cell volume distribution width-standard deviation(RDW-SD),PLT,mean platelet volume(MPV),thrombocyte hematocrit(PCT),platelet large cell ratio(P-LCR),and platelet distribution width(PDW)of elderly apparent healthy population in Suining area.The corresponding reference intervals were:40.3-52.6fL,11.9%-15.1%,(96-284)×10⁹/L,10.8-23.5fL,23.3%-60.8%,0.12%-0.32%,and 9.7-14.6fL,respectively.The reference interval of PLT of elderly apparently healthy population in Suining area was consistent with that of Chengdu area,while there were certain differences with Beijing,Shanghai and other areas.Conclusion The reference intervals for blood cell analysis of healthy elderly people in China provided in Table 7 in the Multicenter Survey of Blood Routine Examination in Apparently Healthy Elderly Population in China are all applicable to the apparently healthy elderly population in Suining area except for PLT.Meanwhile,there are certain differences in the reference intervals of PLT among different regions.Each laboratory should focus on the suitability of the PLT reference interval when verifying the reference interval.