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| 五味子藤化学成分研究 | |
| 引用本文： | 叶丹丹,梁会娟,袁永亮,李婷,白素平.五味子藤化学成分研究[J].新乡医学院学报,2013,30(5):329-331,336. |
| 作者姓名： | 叶丹丹 梁会娟 袁永亮 李婷 白素平 |
| 作者单位： | 1. 新乡医学院药学院,河南新乡,453003 2. 新乡医学院第三附属医院药剂科,河南新乡,453003 3. 中国药科大学药学院,江苏南京,210009 |
| 基金项目： | 国家自然科学基金资助项目，河南省科技创新杰出青年基金资助项目 |
| 摘 要： | 目的研究五味子藤茎的化学成分,为进一步研究其生物活性提供依据。方法利用硅胶柱层析进行分离和纯化化合物,用波谱分析方法鉴定其结构。结果从五味子藤茎中分离得到5个化合物,其中3个倍半萜:6β,8β-二羟基艾里莫芬-7(11)-烯-12,8α-内酯(1)、6β,8α-二羟基里艾莫芬-7(11)-烯-12,8β-内酯(2)、Bullatantriol(3);1个异黄酮:大豆素(4);1个有机酸:反式肉桂酸(5)。结论化合物1和2为首次从五味子属植物中分离得到。 |
| 关 键 词： | 五味子 化学成分 倍半萜 |
Chemical constituents of Schisandra chinensis |
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| YE Dan-dan,LIANG Hui-juan,YUAN Yong-liang,LI Ting,BAI Su-ping.Chemical constituents of Schisandra chinensis[J].Journal of Xinxiang Medical College,2013,30(5):329-331,336. | |
| Authors: | YE Dan-dan LIANG Hui-juan YUAN Yong-liang LI Ting BAI Su-ping |
| Institution: | 1(1.School of Pharmacy,Xinxiang Medical University,Xinxiang 453003,Henan Province,China;2.Department of Pharmacy,the Third Affiliated Hospital of Xinxiang Medical University,Xinxiang 453003,Henan Province,China;3.Pharmacy College of China Pharmaceutical University,Nanjing 210009,Jiangsu Province,China) |
| Abstract: | Objective To study the chemical composition of Schisandra chinensis and provide guidance for further investigation of its bioactivity.Methods Compounds were separated and purified by silica gel column chromatography and their structures were determined by spectroscopic methods.Results Five compounds were isolated and identified from Schisandra chinensis.Three of them were sesquiterpenoids 6β,8β-dihydroxyeremophil-7(11)-en-12,8α-olide(1),6β,8α-dihydroxyeremophil-7(11)-en-12,8β-olide(2),Bullatantriol(3);one was isoflavonoid Daidzein(4),and the other one was trans-Cinnamic acid(5).Conclusion Compounds 1 and 2 were separated from Schisandra chinensis for the first time. |
| Keywords: | Schisandra chinensis chemical constituent sesquiterpenoid |
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