长托宁治疗急性有机磷农药中毒的临床分析

目的：比较长托宁替代阿托品治疗急性有机磷农药中毒临床疗效。方法：急性有机磷农药中毒患者随机分为长托宁治疗组及阿托品对照组。采用推荐剂量分组治疗。治疗组采用长托宁治疗急性有机磷农药中毒患者30例，并与对照组传统方法治疗的30例患者进行比较，观察长托宁用量、CHE恢复时间、住院天数、症状消失时间、反跳率、死亡率和治愈率。结果：与对照组比较，治疗组CHE恢复时间、住院天数、症状消失时间、反跳率和死亡率明显降低（P〈0．01），治愈率明显升高（P〈0．01）。结论：长托宁疗效确实、可靠，是替代阿托品救治有机磷农药中毒的理想药物。

Clinical analysis of treatment by Penehyclidine Hydrochloride Injection for acute organophosphor pesticide toxicosis

Objective：To compare the clinic curative effect of penahyclidine blydrocloride Injective PHI and atropine for acute organophosohor prsticide toxie＇osis.Methods：We divided the sufferers into PHI group and atropine group at random and adopted recommendatory dosage to treat.Results：We compareed the 30 cases of PHI group with the 30 cases of traditional treatment group and observed the PHI dosage, recover time of CHE, days in hospital, disappearance time of symptom, rate of bounce, death rate and cure rate. According to the comparison, all of the recover time of CHE,days in hospital,disappearance time of symptom, rate of bounce and death rate reduced obviously （P〈0.05） and the cure rare increased obviously.Conclusion ：The curative effect of PHI is indubitable and reliable. It is the ideal suecedaneum for atropine.