| 全血胆碱酯酶活性变化与急性有机磷农药中毒程度的相关性研究 |
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| 引用本文： | 庄福聚,李萍,王香,孙斌.全血胆碱酯酶活性变化与急性有机磷农药中毒程度的相关性研究[J].中原医刊,2013(23):40-41. |
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| 作者姓名： | 庄福聚 李萍 王香 孙斌 |
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| 作者单位： | [1]滨州医学院附属医院急诊科,山东滨州256603 [2]滨州医学院附属医院儿科,山东滨州256603 |
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| 摘 要： | 目的探讨全血胆碱酯酶（CHE）活性变化与急性有机磷农药中毒（AOPP）程度之间的关系。方法对186例急诊科住院的急性有机磷农药中毒患者进行动态CHE活性监测，比较胆碱酯酶水平与中毒程度的相关性。结果186例AOPP患者入院时有45％CHE变化与中毒程度成正相关，55％患者CHE变化与中毒程度不符。结论胆碱酯酶活性不宜作为中毒程度的划分和治疗指征的重要指标。
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| 关 键 词： | 急性中毒 胆碱酯酶活性 有机磷农药 |
Correlation study of the activity changes of whole blood cholinesterase and the degree of intoxication of acute organophosphorus pesticide poisoning |
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| ZHUANG Fu-ju,LI Ping,WANG Xiang,SUN Bin.Correlation study of the activity changes of whole blood cholinesterase and the degree of intoxication of acute organophosphorus pesticide poisoning[J].Central Plains Medical Journal,2013(23):40-41. |
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| Authors: | ZHUANG Fu-ju LI Ping WANG Xiang SUN Bin |
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| Institution: | . (Department of Emergency,Affiliated Hospital of Binzhou Medical University ,Binzhou 256603 ,China) |
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| Abstract: | Objective To investigate the relationship between whole blood cholinesterase （CHE） and the varying degrees of disease severity in acute organophosphorus pesticide poisoning （AOPP）. Methods A total of 186 patients with acute organophosphorus pesticide poisoning were re-cruited. The CHE activity and degrees of poisoning were continously monitored, and approached the cor-relations of them. Results CHE change of 83 cases （45 % ） was positively correlated with the degree of intoxication on admission, CHE changes toxication. Conclusions Cholinesterase of toxicity and therapeutic indications of the other 55% patients was inconsistent with the degree of in-activity levels should not be considered as an important indicator |
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| Keywords: | Acute poisoning Cholinesterase activity Organophosphorus pesticide |
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