MAL64 c is a global regulator of α-glucoside fermentation: identification of a new gene involved in melezitose fermentation |
| |
Authors: | Edward L. Perkins Richard B. Needleman |
| |
Affiliation: | (1) Department of Biochemistry, Wayne State University School of Medicine, 540 E. Canfield Avenue, 48201 Detroit, MI, USA |
| |
Abstract: | Summary Maltase constitutive mutants at the MAL6 locus have been mapped to the newly identified regulatory gene MAL64c. We show here that MAL64c has in addition pleiotropic effects on sugar fermentation: MAL64c strains constitutively synthesize an -methylglucosidase and can complement a new gene, MTP1, for the fermentation of melezitose and -methylglucoside. MTP1, maps near MAL1, and either encodes a permease which transports melezitose, -methylglucoside, and maltose or regulates the activity of such a permease. This work shows that MAL64c, a trans-acting regulatory gene, is a global regulatory gene affecting several different pathways of -glucoside metabolism. |
| |
Keywords: | Yeast regulation Maltose Melezitose MAL6 |
本文献已被 SpringerLink 等数据库收录! |
|