| 冠状动脉血管成形术中药物性预适应的应用 |
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| 引用本文： | 单亮,王景峰,廉哲勋,郑方胜.冠状动脉血管成形术中药物性预适应的应用[J].心血管病学进展,2007,28(5):792-795. |
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| 作者姓名： | 单亮 王景峰 廉哲勋 郑方胜 |
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| 作者单位： | 青岛大学医学院附属医院心内科,山东,青岛,266003 |
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| 摘 要： | 预适应的概念发现以来,发现它是对抗心肌缺血的有效机制之一,经皮经腔冠脉成形术中反复球囊扩张是探讨预适应现象的最好的临床模型,也可以用于对预适应模拟药物作用的研究,如腺苷、尼可地尔、缓激肽、氨茶碱、硝酸甘油、尼索地平等。模拟预适应药物的应用可对抗心肌缺血,减少梗死面积,改善预后。
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| 关 键 词： | 缺血预适应 药物性预适应 血管成形术 |
| 文章编号： | 1004-3934（2007）05-0792-04 |
| 修稿时间： | 2006-11-302007-02-28 |
Applications of Pharmacological Preconditioning in Angioplasty |
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| SHAN Liang,WANG Jing-feng,LIAN Zhe-xun,ZHENG Fang-sheng.Applications of Pharmacological Preconditioning in Angioplasty[J].Advances in Cardiovascular Diseases,2007,28(5):792-795. |
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| Authors: | SHAN Liang WANG Jing-feng LIAN Zhe-xun ZHENG Fang-sheng |
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| Institution: | Department of Cardiology, The Affiliated Hospital of Medical College, Qingdao University,Qingdao 266003, China |
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| Abstract: | Ischemic preconditioning is an effective mechanism against myocardial ischemic insults.Repetitive coronary occlusions by balloon inflation during elective percutaneous transluminal coronary angioplasty represent the best clinical model to discuss preconditioning phenomenon.It can also be used to discuss the effect of drugs inducing pharmacological preconditioning,such as adenosine,nicorandil,aminophylline,bradykinin,nisoldipine,and nitroglycerin.Preconditioning-mimetic drugs can be used against myocardial ischemia,reduce the scale of infarction and improve outcomes. |
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| Keywords: | ischemic-preconditioning pharmacological-preconditioning angioplasty |
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