| 翼状胬肉发病机制研究进展 |
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| 引用本文： | 喻谦,柳林.翼状胬肉发病机制研究进展[J].眼科研究,2008,26(9). |
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| 作者姓名： | 喻谦 柳林 |
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| 作者单位： | 第二军医大学第一附属医院眼科,上海,200433 |
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| 摘 要： | 翼状胬肉的病因复杂,相关学说众说纷纭.紫外线辐射的病因学说通过流行病学及其组织病理学改变两个方面得到证实.研究表明其发病机制可能与某些细胞因子的异常表达、正常细胞凋亡程序的破坏及p53基因突变等有关.对翼状胬肉发病机制在细胞因子及分子生物学方面的研究进展进行综述.
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| 关 键 词： | 翼状胬肉 发病机制 紫外线 |
Progress in study on pterygium pathogenesis |
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| Yu Qian,Liu Lin.Progress in study on pterygium pathogenesis[J].Chinese Ophthalmic Research,2008,26(9). |
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| Authors: | Yu Qian Liu Lin |
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| Institution: | Yu Qian,Liu Lin.Department of Ophthalmology,Affiliated Hospital,Second Military Medical University of PLA,Shanghai 200433,China |
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| Abstract: | The pterygium pathogenesis is very comprehensive and shows many controversy views about it.The mechanism of pterygium formation is not completely understood.Epidemiology and histopathology data indicate a positive link between pterygium and ultraviolet radiation.Recent data have provided evidence implicating photoxicity,oxidative damage,aberrant expression of cytokines in the pathogenesis of this disease.Many cytokine(such as VEGF and b-FGF,Cycloxygenase-2,Interleukins)and p53 gene mutation are overexpresse... |
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| Keywords: | p53 |
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