| 光纤药物溶出度实时测定仪监测阿苯达唑片的溶出度 |
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| 引用本文： | 谢军,张涛,廖海燕,杨晶晶,钟元高.光纤药物溶出度实时测定仪监测阿苯达唑片的溶出度[J].药物与人,2014(7):49-49. |
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| 作者姓名： | 谢军 张涛 廖海燕 杨晶晶 钟元高 |
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| 作者单位： | 成都军区总医院药剂科,四川成都610083 |
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| 摘 要： | 目的：建立考察阿苯达唑片溶出过程的方法,初步评价该制剂的内在质量。方法：采用光纤药物溶出仪实时监测阿苯达唑片的溶出过程。结果：所测样品在45min内全部合格,批间和批内差异均较小。结论：光纤溶出仪能够实时有效地测定固体药物的体外溶出度,并能客观反应药物溶出的全过程。
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| 关 键 词： | 阿苯达唑片 溶出度 光纤药物溶出仪 |
The process monitoring of the dissolution of Albendazole tablets with Fiber--optic Medicine dissolution process real time test system |
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| Authors: | XIE Jun ZHANG Tao LIAO Hai-yan YANG Jing-jing ZHONG Yuan-gao |
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| Institution: | 1.Department of Pharmacy, General Hospital of Cheng du Military Command, Chengdu 610017 ,China 2. lnstitute for Drug and Instrument Control of Cheng du Military Region, Chengdu 610017 ,China 3.Department of Pharmacy, Hospital 44 of the PLA, Gulyang 550009,China) |
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| Abstract: | Objective： To establish a method for the whole process of dissolution of Albendazole tablets,Preliminary evaluation of the domestic quality of this preparation. Methods：The release process of Albendazole tablets was determined with fiber--optic medicine dissolution process real time test system. Results： The measured samples are qualified within 45 min,Between batch and batch differences are small Conclusion;This process analysis can refilct the dissolution of solid medicine. And can reflect the whole process of the medicine dissolution. |
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| Keywords: | Albendazole tablets dissolutior fiber-optic medicine dissolution process test |
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