年轻妇女子宫内膜癌预后相关因素分析

目的探讨年轻妇女子宫内膜癌预后相关因素。方法回顾性分析2008年3月至2011年3月收治的年龄<40岁的年轻妇女子宫内膜癌患者185例,根据随访3年后的最终结果分为死亡组与生存组,对临床资料、预后相关因素进行分析。结果经随访3年发现,年轻妇女子宫内膜癌患者3年生存率为87.3%。死亡组与生存组患者比较,在BMI、ER(+)、PR(+)、合并PCOS、病理分期、肌层浸润深度、宫颈浸润情况和淋巴结转移方面差异有统计学意义(P<0.05)。结论 BMI、ER(+)、PR(+)、病理分期、淋巴结转移是影响子宫内膜癌预后的独立危险因素,BMI较大,ER(+)及PR(+)率较低,病理分期较晚,且有淋巴结转移的患者预后可能较差。

Analysis of prognostic factors of young women with endometrial cancer

Objective To investigate the related factors of young women with endometrial cancer prognosis.Methods 185 cases with endometrial cancer from March 2008 to March 2011 in our hospital were chosen,who were young than 40 years old,according to the end result prognosis,who were divided into 2 groups（ the death group and survived group）.The clinical material and prognostic factors were analyzed.Results The 3-year survived rate of young women with endometrial cancer was 87.3% after followed up for 3 years.BMI,ER（ ＋）,PR（ ＋）,combined with PCOS,staging,myometrial invasion,cervical infiltration and lymph node metastasis in death group and survived group had no significant differences（ P〈 0.05）.BMI,ER（ ＋）,PR（ ＋）,staging and lymph node metastasis were independent risk factors of endometrial cancer prognosis.Conclusion BMI,ER（ ＋）,PR（ ＋）,staging and lymph node metastasis were independent risk factors of endometrial cancer prognosis.The prognosis of patients with higher BMI,lower ER（ ＋） and PR（ ＋）,later staging and lymph node metastasis could be poor.