磷酸肌酸钠治疗婴幼儿轮状病毒肠炎并心肌损害疗效观察

目的：观察磷酸肌酸钠治疗婴幼儿轮状病毒肠炎并心肌损害的疗效。方法：将120例轮状病毒肠炎并心肌损害的患儿,随机分为对照组60例与治疗组60例,两组均给予补液、抗感染、纠正水电解质紊乱、酸中毒及对症治疗,在此基础上对照组加用大剂量维生素C、能量合剂等常规治疗。治疗组加用磷酸肌酸钠治疗,疗程均为7d。结果：治疗组患儿的心肌酶、心肌肌钙蛋白I（cTnI）下降快于对照组,心电图恢复正常率、总有效率高于对照组,两组差异均有统计学意义（P〈0.05）。结论：磷酸肌酸钠治疗婴幼儿轮状病毒性肠炎并心肌损害安全有效,值得临床推广应用。

Curative effect of creatine phosphate sodium on infantile rotavirus enteritis and myocardial damage

Objective： To observe the curative effect of creatine phosphate sodium on infantile rotavirus enteritis and myocardial damage. Methods： 120 cases of rotavirus gastroenteritis and myocardial damage infants were randomly divided into control group 60 cases and treatment group 60 cases, all of them were treated with rehydration, antibiotics, correct water and electrolyte disturbance, acidosis, and symptomatic treatment, on this basis, the control group received large doses of vitamin C, and mixture of energy and other conventional treatments. Treatment group received creatine phosphate sodium treatment. The therapeutic courses both groups were 7 days. Results： The enzyme, cardiac troponin I （cTnI） of the control group fell faster than the control group, the rates of ECG returned to normal, total efficiency was higher than the control group, there was significant difference between the two groups （P〈0.05）. Conclusion： Creatine phosphate sodium treatment of infantile rotavirus enteritis and myocardial damage is safe and effective, it is worthy of clinical application.