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复方醛基消毒剂对枯草杆菌黑色变种芽胞杀灭试验的观察
引用本文:王冰姝,陈惠珍,钟昱文,黄美卿,柯昌文.复方醛基消毒剂对枯草杆菌黑色变种芽胞杀灭试验的观察[J].中国卫生检验杂志,2007,17(3):433-434.
作者姓名:王冰姝  陈惠珍  钟昱文  黄美卿  柯昌文
作者单位:广东省疾病预防控制中心,广州,510300
摘    要:目的:研究复方醛基消毒剂杀菌效果。方法:采用载体定量杀菌试验等方法在实验室进行试验观察。结果:醛基含量14300mg/L,二癸基二甲基氯化铵含量20600mg/L的消毒液对载体上枯草杆菌黑色变种芽胞作用4h,杀灭对数值〉3.00。对医疗器械模拟现场消毒试验表明,醛基含量14300mg/L,二癸基二甲基氯化铵含量20600mg/L的消毒液对染于医用止血钳上的枯草杆菌黑色变种芽胞作用4h,杀灭对数值〉3.00;对医疗器械模拟现场灭菌试验表明,同样含量的消毒液作用染菌的医用止血钳5h,可达到灭菌效果。连续使用2周后,作用5h仍可达到灭菌要求。对不锈钢基本无腐蚀,对铝、铜有轻度腐蚀,对碳钢有中度腐蚀。结论:复方醛基消毒剂对枯草杆菌黑色变种芽胞的杀灭效果较杆对余属腐忡忡拧小.

关 键 词:复方醛基  枯草杆菌黑色变种芽胞  医疗器械消毒  医疗器械灭菌  腐蚀性
文章编号:1004-8685(2007)03-0433-02
收稿时间:2006-09-04
修稿时间:2006年9月4日

Experimental observation of killing efficacy of compound aldehyde group disinfectant to medical instruments
Wang Bing-shu,Chen Hui-zhen,Zhong Yu-wen,Huang Mei-qing,Ke Chang-wen.Experimental observation of killing efficacy of compound aldehyde group disinfectant to medical instruments[J].Chinses Journal of Health Laboratory Technology,2007,17(3):433-434.
Authors:Wang Bing-shu  Chen Hui-zhen  Zhong Yu-wen  Huang Mei-qing  Ke Chang-wen
Institution:Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 510300, China
Abstract:Objective:To study germicidal efficacy of compound aldehyde group disinfectant.Methods:Carrier quantitatives germicidal tests were used to carry out the laboratory observations.Results:The reduction factor(log10) of Bacillus subtilis var.niger spores exposed to the disinfectant solution containing aldehyde group 14 300 mg/L and dimethyldidecyl ammonium chloride 20 600 mg/L for 4 hours was more than 3.00.It was proved,in the disinfectant experiment of analog scene of medical instruments,that the reduction factor(log10) of Bacillus subtilis var.niger spores contaminating medical haemostat exposed to the disinfectant solution containing aldehyde group 14 300 mg/L and dimethyldidecyl ammonium chloride 20 600 mg/L for 4 hours was more than 3.00;and in the germicidal expieriment of analog scene of medical instruments,it showed that the same content disinfection solution had sterilizing effect when it was used to the contaminated medical haemostat for 5 hours.After being continuously used 2 weeks,it could still meet with the germicidal requirement.This compound aldehyde group disinfectant had less causticity to metal.There are no caustic for stainless steel,middle-class caustic for mild steel,and low-class caustic for aluminium and copper.Conclusion:Aldehyde group disinfectant has good efficacy in killing spores of Bacillus subtilis var.niger,and slight corrosive effect on metal.
Keywords:Bacillus subtilis var  niger spore  Medical instrument disinfection  Medical instrument sterilization  Causticity
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