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Integrated Hedgehog signaling is induced following castration in human and murine prostate cancers
Authors:Eleni Efstathiou  Maria Karlou  Sijin Wen  Anh Hoang  Curtis A. Pettaway  Louis L. Pisters  Sankar Maity  Patricia Troncoso  Christopher J. Logothetis
Affiliation:1. Department of Clinical Therapeutics, University of Athens Medical School, Athens, Greece;2. Department of Genitourinary Medical Oncology, David H. Koch Center for Applied Research of Genitourinary Cancers, Houston, Texas;3. Departments of Genitourinary Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas;4. Departments of Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas;5. Departments of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas;6. Departments of Urology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Abstract:
Keywords:prostate cancer  preoperative treatment  Hedgehog signaling  resistance to treatment  androgen ablation
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