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Identification of recurrent FGFR3 fusion genes in lung cancer through kinome‐centred RNA sequencing
Authors:Ian J Majewski  Lorenza Mittempergher  Nadia M Davidson  Astrid Bosma  Stefan M Willems  Hugo M Horlings  Iris de Rink  Liliana Greger  Gerrit KJ Hooijer  Dennis Peters  Petra M Nederlof  Ingrid Hofland  Jeroen de Jong  Jelle Wesseling  Roelof JC Kluin  Wim Brugman  Ron Kerkhoven  Frank Nieboer  Paul Roepman  Annegien Broeks  Thomas R Muley  Jacek Jassem  Jacek Niklinski  Nico van Zandwijk  Alvis Brazma  Alicia Oshlack  Michel van den Heuvel  René Bernards
Institution:1. Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, , 1066 CX Amsterdam, The Netherlands;2. Division of Cancer and Haematology, The Walter and Eliza Hall Institute, , Parkville, Victoria, 3052 Australia;3. Bioinformatics Group, Murdoch Childrens Research Institute, Royal Children's Hospital, , Parkville, Victoria, 3052 Australia;4. Department of Pathology, University Medical Centre Utrecht, , 3584 CX Utrecht, The Netherlands;5. Department of Pathology, Academic Medical Centre, , 1105 AZ, Amsterdam, The Netherlands;6. Genomics Core Facility, The Netherlands Cancer Institute, , 1066 CX Amsterdam, The Netherlands;7. European Bioinformatics Institute, EMBL‐EBI, , Hinxton, Cambridge, CB10 1SD UK;8. Core Facility for Molecular Pathology & Biobank, Department of Molecular Pathology, The Netherlands Cancer Institute, , 1066 CX Amsterdam, The Netherlands;9. Department of Pathology, The Netherlands Cancer Institute, , 1066 CX Amsterdam, The Netherlands;10. Agendia BV, , 1098 XH Amsterdam, The Netherlands;11. Translational Research Unit, Thoraxklinik at the University Hospital Heidelberg, Heidelberg, Germany & Translational Lung Research Centre Heidelberg (TLRC‐H), Member of the German Centre for Lung Research (DZL);12. Department of Oncology and Radiotherapy, Medical University of Gdansk, , Gdansk, Poland;13. Department of Thoracic Surgery, Medical University of Bialystok, , Bialystok, Poland;14. Asbestos Diseases Research Institute, , New South Wales, Australia;15. Department of Thoracic Oncology, The Netherlands Cancer Institute, , 1066 CX Amsterdam, The Netherlands
Abstract:
Keywords:kinome  fusion genes  FGFR3  ALK  FGFR3–  TACC3
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