Improved Bloch‐Siegert based B1 mapping by reducing off‐resonance shift |
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Authors: | Qi Duan Peter van Gelderen Jeff Duyn |
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Affiliation: | Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, , Bethesda, Maryland, USA |
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Abstract: | An MRI method based on the Bloch‐Siegert (BS) shift phenomenon was recently proposed as a fast and precise way to map a radio frequency (RF) transmit field (B1+ field). For MRI at high field, the mapping sensitivity of this approach was limited by tissue heating associated with a BS irradiation pulse. To mitigate this, we investigated the possibility of lowering the off‐resonance frequency of this pulse since theoretical analysis indicated that the sensitivity of Bloch‐Siegert based B1+ mapping could be substantially improved when irradiating closer to resonance. Using optimized irradiation pulse shape and gradient crushers to minimize direct excitation effects, in vivo experiments on human brains at 7 T confirmed improved sensitivity with this approach. Improved sensitivity translated into an 80% reduction in B1+ estimation errors without increasing tissue heating. Published 2013. This article is a U.S. Government work and is in the public domain in the USA. |
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Keywords: | high field MRI flip angle wavelength effects B1 mapping transmit sense |
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