穴位针刺效应启动子研究进展及评述

穴位局部作为针刺刺激信息的初始应答部位,对针效的发挥起着至关重要的作用。我们认为针刺效应产生的整个过程由下列主要环节构成:针刺信息穴位局部启动,外周及中枢复杂网络的传导、协调或整合及靶器官的响应。多年来针灸作用机制研究结果表明,针刺可引起穴位局部微环境发生特异性的应答变化,包括细胞功能的激活,化学物质的释放,传入神经的兴奋,这可能构成了穴位局部针效信息启动子重要的生物学基础。

Progress of Researches and Comments on Promoters Initiating Effects of Acupuncture Stimulation of Acupoints

Acupoints,the local initial site of signals of acupuncture or moxibustion stimulation,play an important role in producing clinical therapeutic effects.The whole process of acupuncture stimulation induced improvement of the related visceral dysfunction or regional disorders includes 3key links:1)initiation of acupuncture/moxibustion signals from the stimulated acupoints;2)conduction,coordination and integration of the complicated peripheral and central networks;and 3)responses of the target organs.Abundant research results indicate that acupuncture or moxibustion stimulation can induce specific changes in the regional micro-environment such as excitement of the peripheral cells,release of chemical substances,excitement of the afferent nerve,etc.,which constitutes the important biological basis of the initial process of regional acupoint signals for producing therapeutic effects.